Jennie Wyse Power (born Jane O’Toole; 1 May 1858 – 5 January 1941) was an Irish activist, feminist, politician and businesswoman. She was a founder member of Sinn Féin and also of Inghinidhe na hÉireann.
She was appointed to the Irish Free State Seanad Éireann as an independent member in December 1922 by the President of the Executive Council. She was one of four women elected or appointed to the first Seanad in 1922. She was elected for 9 years in 1934 and served until the Seanad was abolished in 1936. She was also a shopkeeper, restaurateur and the founder of the Irish Farm Produce Company. Her husband, John Wyse Power, was one of the founding members of the GAA.
The Wyse Powers appear as the Wyse Nolans in “Ulysses” by James Joyce.
In 1991, the 1916-21 Club marked the home and business premises of Jennie Wyse Power at 21 Henry Street with a plaque.